4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, also known as DMTMM, is an alcohol and water-soluble coupling reagent used to synthesise amides and esters in a one-step procedure. DMTMM is selective, achieves good yields and can be easily removed under reduced pressure from the reaction mixture. DMTMM finds application in the activation of carboxyl polysaccharides to make glucans, in the functionalisation of poly(acrylic acid) and poly(methacrylic acid) with amines via amide bonds, to make glycoconjugates and for coupling propylamine and butylamine to hyaluronic acid. Synonyms: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium Chloride, DMTMM, MMTM CAS Number: 3945-69-5 Molecular Formula: C10H17ClN4O3 Molecular Weight: 276.72 Purity: 95% Appearance: White to off-white solid Solubility: Methanol (Sparingly) Method for Determining Identity: Proton NMR Spectroscopic and Mass Spectrometric Analysis TLC Conditions: SiO2: Dichloromethane: Methanol: 9:1, Visualized with UV, Single Spot, Rf=0.40 Chloride Content: As Reported Elemental Analysis: Calculated: %C: 43.40, %H: 6.19, %N: 20.25 2,4,6-trimethoxy-1,3,5-triazine Content: As Reported Storage and Stability: Store at 4C. Stable for 6 months after receipt. Hygroscopic. Keep tightly closed and desiccated. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
276.72
CAS Nummer:
[3945-69-5]
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