N-(2-(Diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide, CAS [[557795-19-4]]

Produktübersicht

• Artikelname: N-(2-(Diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide, CAS [[557795-19-4]]
• Artikelnummer: USB-273137
• Hersteller Artikelnummer: 273137
• Alternativnummer: USB-273137-500, USB-273137-1, USB-273137-2, USB-273137-5, USB-273137-10
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

Sunitinib (as the malate salt) is the active ingredient in the drug sold under the trade name Sutent. This drug is a small molecule receptor tyrosine kinase inhibitor that has been approved in at least one country for the treatment of patients having gastrointestinal stromal tumors or renal cell carcinomas. Synonyms: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide, SU-11248, Sutent, PHA-290940AD, PNU-290940AD CAS No: 557795-19-4 Molecular Formula: C22H27FN4O2 Molecular Weight: 398.47 Appearance: Yellow powder Purity: 99% Solubility: Soluble Solubility: Soluble Solubility: Soluble in DMSO at 40mg/ml, soluble in ethanol at 1.4mg/ml with warming, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10-20uM, buffers, serum, or other additives may increase or decrease the aqueous solubility. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Produkteigenschaften

• Molekulargewicht: 398.47
• CAS Nummer: [557795-19-4]