Fmoc-O-tert-butyl-L-trans-4-hydroxyproline is a synthetic, cleavable peptide that can be used as a biomaterial. It is synthesized by coupling Fmoc-O-(tert-butoxycarbonyl)-L-trans(4R)-hydroxyproline with the amino acid N,N-diisopropylcarbodiimide and 4-(dimethylamino)pyridine in a microwave reactor. The peptide has been shown to inhibit the enzyme matrix metalloproteinase 9 (MMP9), which plays an important role in tumor cell invasion and metastasis. This compound also has the ability to form conjugates with other molecules, such as lipopeptides, which may improve its therapeutic potential. Synonyms: Fmoc-L-Hyp(tBu)-OH, (2S-trans)-4-(1,1-Dimethylethoxy)-1,2-Pyrrolidinedicarboxylic Acid 1-(9H-fluoren-9-ylmethyl) Ester CAS No: 122996-47-8 Molecular Formula: C24H27NO5 Molecular Weight: 409.47 Purity: 98% (HPLC) Appearance: White to off-white powder 1H-NMR Spectrum: Conforms to reference Melting Point: 63C (lit) Water (KF): 2% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. Stable for 6 months after receipt.
Molekulargewicht:
409.47
CAS Nummer:
[122996-47-8]
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