A metabolite of Methotrexate, which is used as a antineoplastic and antirheumatic. Synonyms: 7-Hydroxy amethopterin, 4-amino-7-hydroxy-10-methylpteroylglutamic acid, N-[4-[[(2,4-Diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid, NSC 380962 CAS No: 5939-37-7 Molecular Formula: C20H22N8O6 Molecular Weight: 470.44 Appearance: Light yellow to light orange solid Purity: 98% Melting Point: >221C (dec.) Solubility: Aqueous Basic (Slightly), DMSO (Slightly, Sonicatedy), Methanol (Slightly) Method for Determining Identity: Proton NMR (DMSO-d6, D2O+ NaOD) Spectroscopic and Mass Spectrometric Analysis TLC Conditions: C18: Acetonitrile: Water: Ammonium Hydroxide=8:2:0.1, Visualized with UV and KMnO4, Single Spot, Rf=0.40 Elemental Analysis: Calculated: %C: 51.06, 5H: 4.71, %N: 23.82 Storage and Stability: Long-term storage is recommended at -20C. Stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
470.44
Reinheit:
98%
Formulierung:
Light yellow to light orange solid
CAS Nummer:
[5939-37-7]
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