| Lysozyme, also known as muramidase, is a bacteriolytic enzyme found in phagocytic cells like leukocytes. The name lysozyme is derived from its ability to dissolve or hydrolyze the beta-1-4-glycosidic bond between N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM) in the walls of certain bacteria. This protein is present in animals, plants, bacteria, and viruses. It can also be found in granules of neutrophils, macrophages, as well as in serum, saliva, milk, honey, and hen egg white. There are different types of lysozymes, including the c-type (chicken type), the g-type (goose-type), and the i-type (invertebrates). Source: chicken egg white EC Number: 3.2.1.17 (BRENDA, IUBMB) Synonyms: Peptidoglycan iV-acetylmuramoyl hydrolase, Mucopeptide N-acetylmuramoylhydrolase, Muramidase, (2S,8S,11S,14S,20S,23S,26S,29S,32S,38S,41S,44S,47S,50S,53S,56S,59S,62S)-38-((1H-imidazol-5-yl)methyl)-62-(((2R,5S,11S,14S)-14-amino-11-benzyl-5-(3-guanidinopropyl)-1,4,7,10,13-pentahydroxy-2-(mercaptomethyl)-15-methyl-3,6,9,12-tetraazahexadeca-3,6,9,12-tetraen-1-ylidene)amino)-44-(4-aminobutyl)-29-(carboxymethyl)-20,41-bis(3-guanidinopropyl)-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61-icosahydroxy-2,26-bis(2-hydroxy-2-iminoethyl)-14,23-bis(4-hydroxybenzyl)-11-(hydroxymethyl)-8,32,59-triisobutyl-50,53,56-trimethyl-47-(2-(methylthio)ethyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60-icosaazapentahexaconta-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60-icosaenedioic acid CAS No: 9066-59-5 Molecular Formula: C125H196N40O36S2 Molecular Weight: ~14.3kD Appearance: Supplied as a lyophilized powder containing sodium chloride and sodium acetate. Purity: 80% Protein Activity: 35,000 units/mg protein Unit Definition: One unit will lyse 0.6ug of Micrococcus lysodeikticus per minute by turbidimetric detection at 600nm when suspended in buffer at pH 6.2 at 25C. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
