| 6alpha-Methylprednisolone 21-Hemisuccinate is a glucocorticosteroid used in anti-inflammatory medication in the treatment of spinal cord injuries. Synonyms: (6alpha,11beta)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-pregna-1,4-diene-3,20-dione, Monosodium Salt, 11beta,17,21-trihydroxy-6alpha-methyl-, 21-(hydrogen succinate)pregna-1,4-diene-3,20-dione Monosodium Salt, 11beta,17,21-trihydroxy-6alpha-methyl-pregna-1,4-diene-3,20-dione 21-(Hydrogen Succinate) Sodium Salt, 6-Methylprednisolone Sodium Succinate, 6alpha-Methylprednisolone 21-Sodium Hemisuccinate, 6alpha-Methylprednisolone 21-Sodium Succinate, 6alpha-Methylprednisolone Sodium Hemisuccinate, 6alpha-Methylprednisolone Sodium Succinate, 6alpha-Methylpregnisolone 21-Sodium Succinate, Methylprednisolone Hemisuccinate Sodium, Methylprednisolone sodium succinate, Methylprednisolone succinate sodium, Metypred, NSC 48989, Sodium Methylprednisolone Succinate, Solu-Medrol, Solu-Medrone, U 9088, Urbason Solubile CAS No: 2375-03-3 Free acid: 2921-57-5 Molecular Formula: C26H33NaO8 Molecular Weight: 496.53 Purity: 98% (HPLC) Appearance: White to off-white solid Melting Point: >190C (dec) Solubility: DMSO (Slightly), Methanol (Slightly) Atmosphere: Inert Gas Method For Determining Identity: Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric analysis TLC Conditions: SiO2, Dichloromethane: Methanol=9:1, Visualized with UV and KMnO4, Single spot, Rf=0.50 Elemental Analysis: Calculated: %C: 62.89, %H: 6.70 Specific Rotation (c=0.2, Methanol): +77.5 Sodium Content: ~4% (by Ion Chromatography) Acetone Content: ~2% Storage and Stability: Long-term storage is recommended at -20C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic. Store under inert atmophere. |
