3-O-Hydroxyethyl-D-glucose (3HEG) is a hexose sugar that can be synthesized from D-glucose and glycerol. It is an important precursor for the synthesis of polyethylene glycols for drug delivery and has been shown to be a potent inhibitor of glucose uptake in Xenopus oocytes. 3HEG is also a good carbon source for cell growth, but it can only be metabolised by cells with the appropriate enzymes. Glucofuranose, which is structurally similar to 3HEG, can inhibit uptake of glucose by binding to glucose transporters on the cell membrane surface. This inhibition may be due to the structural similarities between these two sugars. Mechanistic studies indicate that this inhibition may occur as a result of competitive inhibition or allosteric modulation, but further research is required to elucidate this mechanism. Synonyms: xxx CAS No: 25018-14-8 Molecular Formula: C8H16O7 Molecular Weight: 224.21 Appearance: White to off-white to yellow powder Purity (HPLC): 98% 1H-NMR: Conforms to reference Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
224.21
Reinheit:
98% (HPLC)
Formulierung:
White to off-white to yellow powder
CAS Nummer:
[25018-14-8]
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