Propranolol-2-O-b-D-glucuronide, CAS [[66322-66-5]]
Artikelnummer:
USB-294456
Hersteller Artikelnummer:
294456
Alternativnummer:
USB-294456-1,USB-294456-5,USB-294456-10
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Propranolol-2-O-b-D-glucuronide is a metabolite of propranolol hydrochloride. It has been shown to have low bioavailability in humans and rats. Propranolol-2-O-b-D-glucuronide is eliminated via the kidney, with an elimination rate that is faster than the parent drug propranolol hydrochloride. The glucuronide conjugate of propranolol, which is found in urine samples, has been shown to be a potential biomarker for glomerular filtration rate and renal function. Synonyms: (R,S)-Propranolol-O-beta-D-glucuronide, 1-[[(1-Methylethyl)amino]methyl]-2-(1-naphthalenyloxy)ethyl beta-D-glucopyranosiduronic acid, (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-((1-(isopropylamino)-3-(naphthalen-1-yloxy)propan-2-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid CAS No: 66322-66-5 Molecular Formula: C22H29NO8 Molecular Weight: 435.47 SMILES: CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O[C H]3[C H](C([C H](C(O3)C(=O)[O-])O)O)O.[Na+] Purity: 95% Appearance: White powder 1H-NMR: Conforms to reference Solubility: DMSO, MeOH Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
435.47
CAS Nummer:
[66322-66-5]
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