S-Adenosyl-L-methionine p-toluenesulfonate, CAS [[52248-03-0]]
Artikelnummer:
USB-295137
Hersteller Artikelnummer:
295137
Alternativnummer:
USB-295137-1,USB-295137-5,USB-295137-10
Hersteller:
US Biological
Kategorie:
Biochemikalien
S-(5'-Adenosyl)-L-methionine (SAM) is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells and colon cancer cells. Methyl donor, cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury. Synonyms: (3S)-5-[(3-Amino-3-carboxylatopropyl)methylsulphonio]-5-deoxyadenosine), SAMe p-toluenesulfonate, S-Adenosylmethionine Tosylate, Adomet, Ademetionine, S-Adenosyl-L-methionine tosylate , 5-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5-deoxy-adenosine tosylate CAS No: 52248-03-0 Molecular Formula: C15H22N6O5SxC7H8O3S Molecular Weight: 570.64 Purity: 95% Appearance: White to off-white solid Solubility: Water: 100mg/ml Melting Point: 70-90C Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
570.64
CAS Nummer:
[52248-03-0]
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