8-Chloroadenosine is a potent nucleoside analog and an active metabolite of 8-chloro cAMP, primarily used in cancer research for its ability to inhibit RNA synthesis and induce apoptosis. As a chlorine derivative of adenosine, it functions as a purine antimetabolite, showing potential antineoplastic activity in various cancers, including leukemia. Synonyms: (2R,3R,4S,5R)-2-(6-amino-8-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, 8-Chloro-D-adenosine, 2-(6-amino-8-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, 2-(6-amino-8-chloro-9-purinyl)-5-(hydroxymethyl)oxolane-3,4-diol CAS No: 34408-14-5 Molecular Formula: C10H12ClN5O4 Molecular Weight: 301.69 Purity: 99% (HPLC) Appearance: White to off-white powder Solubility: Water: 20mM, DMSO: 100mM Melting Point: 189-191C (lit) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
301.69
CAS Nummer:
[34408-14-5]
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