Beta-Aescin (also known as beta-escin) is a saponin produced by the horse chestnut tree, Aesculus hippocastanum, with most published reports relating to the pharmacological properties that it shows. It is reported that beta-aescin is a safe and very tolerable drug in the treatment of post thrombotic syndrome and chronic venous insufficiency. Aescin shows promise in the treatment of arthritis and appears to have potential as an anti-cancer drug. In fact, beta-aescin is active on glioblastoma-initiating cells (GIC), which have the ability to initiate glioblastoma growth. Glioblastoma multiform is the most abundant primary tumor of the human nervous system. Beta-aescin was more efficient in diminishing GIC growth compared to present clinically used drugs. Synonyms: 3-(4-O-beta-D-glucopyranosyl-2-O-beta-D-xylopyranosyl-beta-D-glucopyranuronoside)escigenin 3-Hydroxy-2-methylbutyrate Acetate, 3,5-Epoxypicene, escin deriv., Oleanane Escin deriv., Aescin, Aescine, Aescusan, Ba 2672, Escusan, Eskuzan, Flebostasin Retard CAS No: 6805-41-0 Molecular Formula: C55H86O24 Molecular Weight: 1131.27 Appearance: White to beige to yellow or gray powder Purity: 98% Melting Point: >205C (dec.) Solubility: DMSO (Slightly, Sonicated), Ethanol (Slightly) Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
1131.27
Reinheit:
98%
Formulierung:
White to beige to yellow or gray powder
CAS Nummer:
[6805-41-0]
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