Integrin beta 7, IgG2, Clone: [15H76], Rat, Monoclonal

Artikelnummer: USB-299165
Artikelname: Integrin beta 7, IgG2, Clone: [15H76], Rat, Monoclonal
Artikelnummer: USB-299165
Hersteller Artikelnummer: 299165
Alternativnummer: USB-299165-50
Hersteller: US Biological
Wirt: Rat
Kategorie: Antikörper
Applikation: FC, WB
Immunogen: Recombinant protein corresponding to mouse Integrin beta 4.
Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions. Applications: Suitable for use in Flow Cytometry, Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000-2000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Klonalität: Monoclonal
Klon-Bezeichnung: [15H76]
Isotyp: IgG2
Reinheit: Purified by Protein G affinity chromatography from culture supernatant.
Formulierung: Supplied as a lyophilized powder in PBS. Reconstitute with 500ul sterile PBS.