BRCA1, Recombinant, Human, His-Tag (Breast Cancer Type 1 Susceptibility Protein, RING Finger Protein 53, RNF53, BROVCA1, IRIS, PNCA4, PSCP)
Artikelnummer:
USB-299321
Hersteller Artikelnummer:
299321
Alternativnummer:
USB-299321-2
Hersteller:
US Biological
Kategorie:
Molekularbiologie
The BRCA1 protein is a tumor suppressor and is directly involved in DNA repair. Mutations in the BRCA1 gene have been implicated in hereditary breast and ovarian cancer. Source: Recombinant protein corresponding to aa1-1863 of wild type human BRCA1, fused to polyhistidine-tag at N-terminal, expressed in Baculovirus. Accession Number: NM_007296 Molecular Weight: ~205kD Applications: Suitable for use in in vitro function studies including transcription and DNA repair, for protein-protein interaction assays and cell growth assays. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
