CaV1.3 (Alpha-1 Polypeptide, CAC1D_HUMAN, CACH3, CACN4, CACNA 1D, CACNA1D, CACNL1A2, Calcium Channel, Calcium Channel L Type alpha 1 Polypeptide Isoform 2, Calcium Channel Neuroendocrine/Brain Type alpha 1 Subunit, Calcium Channel
Artikelnummer:
USB-303188
Hersteller Artikelnummer:
303188
Alternativnummer:
USB-303188-100
Hersteller:
US Biological
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Immunogen:
Recombinant protein corresponding to human CaV1.3 expressed in E. coli. (Position: M1-I180). Species sequence homology: mouse (99%) and rat (98%)
CACNA1D is also known as PASNA, SANDD or Cav1.3. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.1-0.5ug/ml, the detection limit is ~0.1ng/lane under reducing conditions. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
