IL1R2 (Interleukin-1 Receptor Type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 Antigen-like Family Member B, CDw121b, IL-1 type II Receptor, Interleukin-1 Receptor beta, IL-1R-beta, Interleukin-1 Receptor Type II, CD121b, Interleukin-1 R
IL1R2 (Interleukin-1 Receptor Type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 Antigen-like Family Member B, CDw121b, IL-1 type II Receptor, Interleukin-1 Receptor beta, IL-1R-beta, Interleukin-1 Receptor Type II, CD121b, Interleukin-1 R
IL1R2 (Interleukin-1 Receptor Type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 Antigen-like Family Member B, CDw121b, IL-1 type II Receptor, Interleukin-1 Receptor beta, IL-1R-beta, Interleukin-1 Receptor Type II, CD121b, Interleukin-1 R
Artikelnummer:
USB-320283
Hersteller Artikelnummer:
320283
Alternativnummer:
USB-320283-50,USB-320283-100
Hersteller:
US Biological
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, IHC
Immunogen:
Fusion protein of human IL1R2
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. Applications: Suitable for use in ELISA, Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1000-1:5000 Immunohistochemistry: 1:25-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
