C-C motif chemokine 20, active (CCL20), Recombinant, Human
Artikelnummer:
USB-347954
Hersteller Artikelnummer:
347954
Alternativnummer:
USB-347954-5
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213. {ECO:0000269|PubMed:12149255}. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 10-50ng/ml. Sequence: ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM Molecular Weight: 8.0kD PubMed ID: 9013939, 9038201, 9129037, 11352563, 15815621, 15489334, 110e35086, 12149255 Gene Name: CCL20,LARC,MIP3A,SCYA20 Swiss Prot: P78556 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
