C-C motif chemokine 23, active (CCL23), Recombinant, Human
Artikelnummer:
USB-347960
Hersteller Artikelnummer:
347960
Alternativnummer:
USB-347960-5
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. {ECO:0000269|PubMed:15905581}. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-50ng/ml. Sequence: RVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN Molecular Weight: 11.4kD PubMed ID: 9104803, 9558365, 10213461, 16625196, 15489334, 9129202, 15905581, 11060285 Gene Name: CCL23,MIP3,MPIF1,SCYA23 Swiss Prot: P55773 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
