C-C motif chemokine 25, active (Ccl25), Recombinant, Mouse
Artikelnummer:
USB-347964
Hersteller Artikelnummer:
347964
Alternativnummer:
USB-347964-5
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 5.0-50ng/ml. Sequence: QGAFEDCCLG YQHRIKWNVL RHARNYHQQE VSGSCNLRAV RFYFRQKVVC GNPEDMNVKR AIRILTARKR LVHWKSASDS QTERKKSNHM KSKVENPNST SVRSATLGHP RMVMMPRKTN N Molecular Weight: 14.1kD PubMed ID: 9285413, 10602049, 16517733, 16141072, 19468303, 15489334 Gene Name: Ccl25,Scya25,Teck Swiss Prot: O35903 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
