C-X-C motif chemokine 3, active (CXCL3), Recombinant, Human
Artikelnummer:
USB-348004
Hersteller Artikelnummer:
348004
Alternativnummer:
USB-348004-10
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. {ECO:0000250, ECO:0000269|PubMed:10095777}. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100ng/ml. Sequence: ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN Molecular Weight: 7.9kD PubMed ID: 2201751, 2217207, 15815621, 15489334, 15340161, 10095777 Gene Name: CXCL3,GRO3,GROG,SCYB3 Swiss Prot: P19876 Storage and Stability: Lyophilized and reconstituted products may be stored at -20C. Stable for 6 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
