Interferon gamma, active (IFNG), Recombinant, Human
Artikelnummer:
USB-348085
Hersteller Artikelnummer:
348085
Alternativnummer:
USB-348085-100, USB-348085-500
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using HT-29 cells is less than 0.05ng/ml, corresponding to a specific activity of > 2.0x10e7 IU/mg. Sequence: MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFRGR RASQ Molecular Weight: 16.9kD PubMed ID: 6180322, 6173769, 2860101, 6329718, 6176945, 19054851, 15489334, 6427223, 3109913, 2504704, 1902591, 7617032, 10860730, 10986460, 1525157, 15327519 Gene Name: IFNG Swiss Prot: P01579 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
