Cytokine that contributes to the inflammatory response in vivo. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.2ng/ml, corresponding to a specific activity of > 5.0x10e6 IU/mg. Sequence: LPVNTRCKLE VSNFQQPYIV NRTFMLAKEA SLADNNTDVR LIGEKLFRGV SAKDQCYLMK QVLNFTLEDV LLPQSDRFQP YMQEVVPFLT KLSNQLSSCH ISGDDQNIQK NVRRLKETVK KLGESGEIKA IGELDLLFMS LRNACV Molecular Weight: 16.6kD PubMed ID: 10657629, 11197690, 15489334 Gene Name: Il22,Il22a,Iltif,Iltifa Swiss Prot: Q9JJY9 Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
