CDK2AP1, Recombinant, Human, aa1-115, His-Tag (Cyclin-dependent kinase 2 associated protein 1)

Produktübersicht

• Artikelname: CDK2AP1, Recombinant, Human, aa1-115, His-Tag (Cyclin-dependent kinase 2 associated protein 1)
• Artikelnummer: USB-349775
• Hersteller Artikelnummer: 349775
• Alternativnummer: USB-349775-10, USB-349775-50, USB-349775-100, USB-349775-250
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Also, interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. Recombinant protein corresponding to aa1-115 from human CDK2AP1, fused to His-tag, expressed in E. coli. Swiss/Uniprot Accession: O14519 Molecular Weight: ~16.6kD Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSY KPNLAAHMPA AALNAAGSVH SPSTSMATSS QYRQLLSDYG PPSLGYTQGT GNSQVPQSKY AELLAIIEEL GKEIRPTYAG SKSAMERLKR GIIHARGLVR ECLAETERNA RS Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 16.6
• NCBI: 004633
• UniProt: O14519
• Reinheit: 95% (SDS-PAGE)
• Formulierung: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 2mM DTT, 50% glycerol.