Nicotinamide riboside kinase 2, also known as ITGB1BP3, belongs to the uridine kinase family and NRK subfamily. ITGB1BP3 is found at lower levels in heart and is downregulated during myoblast differentiation. ITGB1BP3 catalyzes the phosphorylation of nicotinic acid riboside and nicotinamide riboside to form nicotinic acid mononucleotide and nicotinamide mononucleotide. Source: Recombinant protein corresponding to aa1-230 of human ITGB1BP3, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~28.4kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMKLIVGI GGMTNGGKTT LTNSLLRALP NCCVIHQDDF FKPQDQIAVG EDGFKQWDVL ESLDMEAMLD TVQAWLSSPQ KFARAHGVSV QPEASDTHIL LLEGFLLYSY KPLVDLYSRR YFLTVPYEEC KWRRSTRNYT VPDPPGLFDG HVWPMYQKYR QEMEANGVEV VYLDGMKSRE ELFREVLEDI QNSLLNRSQE SAPSPARPAR TQGPGRGCGH RTARPAASQQ DSM Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
