MEMO1, Recombinant, Human, aa1-297, His-Tag (Mediator of ErbB2-driven cell motility 1, C2orf4, NS5ATP7, Protein MEMO1)
Artikelnummer:
USB-350071
Hersteller Artikelnummer:
350071
Alternativnummer:
USB-350071-100,USB-350071-500
Hersteller:
US Biological
Kategorie:
Molekularbiologie
MEMO1 (Mediator of ErbB2-driven cell motility 1), also known as C2orf4 or NS5ATP7, belongs to the uPF0103 family. MEMO1 control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. It is required for breast carcinoma cell migration, suggesting an important role in tumorigenesis. Also, it controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. Source: Recombinant protein corresponding to aa1-297 of human MEMO1 fued to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~36.4kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMMSNRV VCREASHAGS WYTASGPQLN AQLEGWLSQV QSTKRPARAI IAPHAGYTYC GSCAAHAYKQ VDPSITRRIF ILGPSHHVPL SRCALSSVDI YRTPLYDLRI DQKIYGELWK TGMFERMSLQ TDEDEHSIEM HLPYTAKAME SHKDEFTIIP VLVGALSESK EQEFGKLFSK YLADPSNLFV VSSDFCHWGQ RFRYSYYDES QGEIYRSIEH LDKMGMSIIE QLDPVSFSNY LKKYHNTICG RHPIGVLLNA ITELQKNGMN MSFSFLNYAQ SSQCRNWQDS SVSYAAGALT VH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
