OLA1, also known as obg-like ATPase 1, functions as a negative regulator of the cellular antioxidant response independent of transcriptional processes. OLA1 suppresses the antioxidant response through nontranscriptional mechanisms. Source: Recombinant protein corresponding to aa1-396 of human OLA1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~47.3kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMPPKKG GDGIKPPPII GRFGTSLKIG IVGLPNVGKS PDERFDFLCQ YHKPASKIPA FLNVVDIAGL VKGAHNGQGL GNAFLSHISA CDGIFHLTRA EEMIGPIIDK LEKVAVRGGD KKLKPEYDIM CKVKSWVIDQ KKPVRFYHDW NDKEIEVLNK IKEWVDKYDP GALVIPFSGA LELKLQELSA EERQKYLEAN MTQSALPKII KAGFAALQLE DFEKGFIMAE VMKYEDFKEE GSENAVKAAG KYRQQGRNYI VEDGDIIFFK FNTPQQPKKK TFFNVLTNSQ ASAENFPFCT IDPNESRVPV FEDDDITHVE GSVDPIRDIE IIHEELQLKD HLFLTSKPMV YLVNLSEKDY IRKKNKWLIK YFFTAGPDEV RAWTIRKGTK APQAAGKIHT Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
