SOSTDC1, Recombinant, Human, aa24-206, His-Tag (Sclerostin Domain-containing Protein 1)
Artikelnummer:
USB-350289
Hersteller Artikelnummer:
350289
Alternativnummer:
USB-350289-100,USB-350289-500
Hersteller:
US Biological
Kategorie:
Molekularbiologie
SOSTDC1 is a member of the sclerostin family and an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. Recombinant protein corresponding to aa24-206 of human SOSTDC1, fused to His-Tag at N-terminal expressed in E. coli. Molecular Weight: ~23kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSFKNDATE ILYSHVVKPV PAHPSSNSTL NQARNGGRHF SNTGLDRNTR VQVGCRELRS TKYISDGQCT SISPLKELVC AGECLPLPVL PNWIGGGYGT KYWSRRSSQE WRCVNDKTRT QRIQLQCQDG STRTYKITVV TACKCKRYTR QHNESSHNFE SMSPAKPVQH HRERKRASKS SKHSMS Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
