TSSK2 is a testis-specific serine/threonine-protein kinase required during spermatid development. This protein phosphorylates TSKS at Ser-288 and SPAG16. TSSK2 involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, it is required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body. Source: Recombinant protein corresponding to aa1-358 of human TSSK2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~43kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDDATVL RKKGYIVGIN LGKGSYAKVK SAYSERLKFN VAVKIIDRKK TPTDFVERFL PREMDILATV NHGSIIKTYE IFETSDGRIY IIMELGVQGD LLEFIKCQGA LHEDVARKMF RQLSSAVKYC HDLDIVHRDL KCENLLLDKD FNIKLSDFGF SKRCLRDSNG RIILSKTFCG SAAYAAPEVL QSIPYQPKVY DIWSLGVILY IMVCGSMPYD DSDIRKMLRI QKEHRVDFPR SKNLTCECKD LIYRMLQPDV SQRLHIDEIL SHSWLQPPKP KATSSASFKR EGEGKYRAEC KLDTKTGLRP DHRPDHKLGA KTQHRLLVVP ENENRMEDRL AETSRAKDHH ISGAEVGKAS T Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
