VTA1, Recombinant, Human, aa1-307, His-Tag (Vacuolar protein sorting-associated protein VTA1 homolog, LIP5, LYST-interacting protein 5, DRG1, Dopamine-responsive protein DRG-1, SBP1, SKD1 binding protein 1)
VTA1, Recombinant, Human, aa1-307, His-Tag (Vacuolar protein sorting-associated protein VTA1 homolog, LIP5, LYST-interacting protein 5, DRG1, Dopamine-responsive protein DRG-1, SBP1, SKD1 binding protein 1)
VTA1, Recombinant, Human, aa1-307, His-Tag (Vacuolar protein sorting-associated protein VTA1 homolog, LIP5, LYST-interacting protein 5, DRG1, Dopamine-responsive protein DRG-1, SBP1, SKD1 binding protein 1)
Artikelnummer:
USB-350392
Hersteller Artikelnummer:
350392
Alternativnummer:
USB-350392-100, USB-350392-500
Hersteller:
US Biological
Kategorie:
Molekularbiologie
VTA1 (Vps20-associated 1 homolog), also known as LIP5 (LYST-interacting protein 5), DRG1 (Dopamine-responsive protein DRG-1), SBP1 (SKD1 bindingprotein 1), belongs to the VTA1 family. This protein Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Also, VTA1 is known to interact with CHMP1B, CHMP2A, CHMP5, VPS4B, KIAA0174 (IST1) and possibly CHMP3. Source: Recombinant protein corresponding to aa1-307 of human VTA1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~36.5kD Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMAALAP LPPLPAQFKS IQHHLRTAQE HDKRDPVVAY YCRLYAMQTG MKIDSKTPEC RKFLSKLMDQ LEALKKQLGD NEAITQEIVG CAHLENYALK MFLYADNEDR AGRFHKNMIK SFYTASLLID VITVFGELTD ENVKHRKYAR WKATYIHNCL KNGETPQAGP VGIEEDNDIE ENEDAGAASL PTQPTQPSSS STYDPSNMPS GNYTGIQIPP GAHAPANTPA EVPHSTGVAS NTIQPTPQTI PAIDPALFNT ISQGDVRLTP EDFARAQKYC KYAGSALQYE DVSTAVQNLQ KALKLLTTGR E Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
