AMIGO2, also known amphoterin-induced protein 2, is a leucine-rich repeat family member. This protein may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. Also, AMIGO2 contributes to signal transduction through its intracellular domain and be required for tumorigenesis of a subset of gastric adenocarcinomas. Source: Recombinant protein corresponding to aa40-398 from human AMIGO2, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~41.9kD (367aa) Amino Acid Sequence: VCPTACICAT DIVSCTNKNL SKVPGNLFRL IKRLDLSYNR IGLLDSEWIP VSFAKLNTLI LRHNNITSIS TGSFSTTPNL KCLDLSSNKL KTVKNAVFQE LKVLEVLLLY NNHISYLDPS AFGGLSQLQK LYLSGNFLTQ FPMDLYVGRF KLAELMFLDV SYNRIPSMPM HHINLVPGKQ LRGIYLHGNP FVCDCSLYSL LVFWYRRHFS SVMDFKNDYT CRLWSDSRHS RQVLLLQDSF MNCSDSIING SFRALGFIHE AQVGERLMVH CDSKTGNANT DFIWVGPDNR LLEPDKEMEN FYVFHNGSLV IESPRFEDAG VYSCIAMNKQ RLLNETVDVT INVSNFTVSR SHAHEAFNTL EHHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
