CTSZ, also known as cathepsin Z/X, is a relatively new cysteine protease of the papain family. Compared to other members of the papain family, CTSZ has a short proregion and unique insertions. Acting as a carboxypeptidase, CTSZ displays a unique specificity. Recombinant protein corresponding to aa23-306 from mouse CTSZ, fused to His-tag at C-terminal expressed in Insect cell. Molecular Weight: ~32.8kD (292aa), ~28-40kD (SDS-PAGE under reducing conditions.) Amino Acid Sequence: ARARLYFRSG QTCYHPIRGD QLALLGRRTY PRPHEYLSPA DLPKNWDWRN VNGVNYASVT RNQHIPQYCG SCWAHGSTSA MADRINIKRK GAWPSILLSV QNVIDCGNAG SCEGGNDLPV WEYAHKHGIP DETCNNYQAK DQDCDKFNQC GTCTEFKECH TIQNYTLWRV GDYGSLSGRE KMMAEIYANG PISCGIMATE MMSNYTGGIY AEHQDQAVIN HIISVAGWGV SNDGIEYWIV RNSWGEPWGE KGWMRIVTST YKGGTGDSYN LAIESACTFG DPIVLEHHHH HH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
