DYNLT3 is a member of a subclass of dynein light chains. This protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. It may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. DYNLT3 may also function independently of dynein as a transcriptional modulator. Source: Recombinant protein corresponding to aa1-116 from human DYNLT3, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~15.5kD (139aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEEYHRH CDEVGFNAEE AHNIVKECVD GVLGGEDYNH NNINQWTASI VEQSLTHLVK LGKAYKYIVT CAVVQKSAYG FHTASSCFWD TTSDGTCTVR WENRTMNCIV NVFAIAIVL Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
