FGF21, also known as fibroblast growth factor 21, is a member of the fibroblast growth factor family. It has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. It stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression. Recombinant protein corresponding to aa29-210 from mouse FGF21, fused to His-tag at C-terminal expressed in Insect cell. Molecular Weight: ~21kD (190aa) Amino Acid Sequence: AYPIPDSSPL LQFGGQVRQR YLYTDDDQDT EAHLEIREDG TVVGAAHRSP ESLLELKALK PGVIQILGVK ASRFLCQQPD GALYGSPHFD PEACSFRELL LEDGYNVYQS EAHGLPLRLP QKDSPNQDAT SWGPVRFLPM PGLLHEPQDQ AGFLPPEPPD VGSSDPLSMV EPLQGRSPSY ASLEHHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
