Flt3 ligand, Recombinant, Human, aa27-184, His-Tag (Fms-related tyrosine Kinase 3 ligand, FLT3LG, Flt3L, FL, SL cytokine)
Artikelnummer:
USB-351224
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| Artikelname: | Flt3 ligand, Recombinant, Human, aa27-184, His-Tag (Fms-related tyrosine Kinase 3 ligand, FLT3LG, Flt3L, FL, SL cytokine) |
| Artikelnummer: | USB-351224 |
| Hersteller Artikelnummer: | 351224 |
| Alternativnummer: | USB-351224-20,USB-351224-50,USB-351224-100,USB-351224-250 |
| Hersteller: | US Biological |
| Kategorie: | Molekularbiologie |
| FLT3LG, also known as fms-related tyrosine kinase 3 ligand, is an alpha-cytokine that promotes the differentiation of multiple hematopoietic cell lineages. Also, this protein acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. FLT3LG is crucial for steady-state pDC and cDC development. It controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts. Recombinant protein corresponding to aa27-184 from human FLT3LG, fused to His-tag at C-terminal, expressed in Baculovirus (insect cell). Swiss/Unprot: P49771 Molecular Weight: ~19kD (166aa) Biological Activity: Measured in a cell proliferation assay using OCI-AML5 acute myeloid leukemia cells. The ED50 range is 5ng/ml. Amino Acid Sequence: TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTAPQPLE HHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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