METRN, also known as meteorin, involved in both glial cell differentiation and axonal network formation during neurogenesis. It promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also, this protein induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Recombinant protein corresponding to aa22-291 from mouse METRN, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~30.2kD (276aa) Amino Acid Sequence: GYSEDRCSWR GSGLTQEPGS VGQLTLDCTE GAIEWLYPAG ALRLTLGGPD PGTRPSIVCL RPERPFAGAQ VFAERMTGNL ELLLAEGPDL AGGRCMRWGP RERRALFLQA TPHRDISRRV AAFRFELHED QRAEMSPQAQ GLGVDGACRP CSDAELLLAA CTSDFVIHGT IHGVAHDTEL QESVITVVVA RVIRQTLPLF KEGSSEGQGR ASIRTLLRCG VRPGPGSFLF MGWSRFGEAW LGCAPRFQEF SRVYSAALTT HLNPCEMALD HHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
