TNFRSF1B, Recombinant, Human, aa23-257, His-Tag (Tumor necrosis factor Receptor superfamily member 1B, CD120b, p75, p75TNFR, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80)

Produktübersicht

• Artikelname: TNFRSF1B, Recombinant, Human, aa23-257, His-Tag (Tumor necrosis factor Receptor superfamily member 1B, CD120b, p75, p75TNFR, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80)
• Artikelnummer: USB-351536
• Hersteller Artikelnummer: 351536
• Alternativnummer: USB-351536-10,USB-351536-50,USB-351536-100,USB-351536-250
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

TNFRSF1B, also known as tumor necrosis factor receptor superfamily member 1B, mediates most of the metabolic effects of TNF-alpha. The receptor isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. Further, high plasma levels of TNFRSF1B were significantly associated with increased incidence of coronary heart disease. Recombinant protein corresponding to aa23-257 from human TNFRSF1B, fused to His-tag at C-terminal expressed in insect cell. Accession Number: NP_001057.1 Molecular Weight: ~25.9kD (241aa) Amino Acid Sequence: LPAQVAFTPY APEPGSTCRL REYYDQTAQM CCSKCSPGQH AKVFCTKTSD TVCDSCEDST YTQLWNWVPE CLSCGSRCSS DQVETQACTR EQNRICTCRP GWYCALSKQE GCRLCAPLRK CRPGFGVARP GTETSDVVCK PCAPGTFSNT TSSTDICRPH QICNVVAIPG NASMDAVCTS TSPTRSMAPG AVHLPQPVST RSQHTQPTPE PSTAPSTSFL LPMGPSPPAE GSTGD Biological Activity: Measured by its ability to inhibit cytotoxicity using L-929 mouse fibroblast cells in the presence of human TNF-alpha. The ED50 range 0.2ug/ml. Applications: Suitable for use in Enzyme Activity and SDS-PAGE. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 25.9
• NCBI: 001057
• UniProt: P20333
• Reinheit: 95% (SDS-PAGE). Endotoxin: 1EU/ug (LAL).
• Formulierung: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.