TXNL4B, also known as Dim2 or DLP, belongs to the DIM1 family that plays an essential role in pro- mRNA splicing. TXNL4B is required in cell cycle progression for S/G2 transition and interact with PRPF6 subunit of the spliceosome. Recombinant protein corresponding to aa1-149 from human TXNL4B, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~21.1kD (185aa) Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSFL LPKLTSKKEV DQAIKSTAEK VLVLRFGRDE DPVCLQLDDI LSKTSSDLSK MAAIYLVDVD QTAVYTQYFD ISYIPSTVFF FNGQHMKVDY GSPDHTKFVG SFKTKQDFID LIEVIYRGAM RGKLIVQSPI DPKNIPKYDL LYQDI Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
