Troponin I, Cardiac, Recombinant, His-Tag (Troponin I, Cardiac muscle, Cardiac Troponin I, TNNI3, TNNC1)
Artikelnummer:
USB-352089
Hersteller Artikelnummer:
352089
Alternativnummer:
USB-352089-1
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Applikation:
ELISA
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Recombinant protein corresponding to full length Troponin I-Cardiac fused to His-tag at N-terminal, expressed in E. coli. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
