CD62P (Antigen CD62, CD62 Antigen Like Family Member P, CD62P Antigen, GMP 140, GMP140, GMP-140, GMRP, GRMP, Granule Membrane Protein 140, Granule Membrane Protein 140kD, LECAM 3, LECAM3, LYAM3, P Selectin, PADGEM, PSelectin, P-Se

Produktübersicht

• Artikelname: CD62P (Antigen CD62, CD62 Antigen Like Family Member P, CD62P Antigen, GMP 140, GMP140, GMP-140, GMRP, GRMP, Granule Membrane Protein 140, Granule Membrane Protein 140kD, LECAM 3, LECAM3, LYAM3, P Selectin, PADGEM, PSelectin, P-Se
• Artikelnummer: USB-353242
• Hersteller Artikelnummer: 353242
• Alternativnummer: USB-353242-100
• Hersteller: US Biological
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC, WB
• Immunogen: Recombinant protein corresponding to W42-G271 of human CD62P, expressed in E. coli. Species sequence homology: mouse (75.2%) and rat (75.7%)

Produktbeschreibung

CD62P is also known as SELP or P-selectin. This gene encodes a 140kD protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 0.1-0.5ug/ml Western Blot: 0.1-0.5ug/ml Immunohistochemistry (paraffin): 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• UniProt: P16109
• Reinheit: Purified by immunoaffinity chromatography.
• Formulierung: Supplied as a lyophilized powder in 5mg BSA, 0.9mg sodium chloride, 0.2mg Na2HPO4, 0.05mg sodium azide. Reconstitute with 200ul sterile dH2O to ~0.5mg/ml.