LY2157299 (LY 2157299, LY-2157299, Galunisertib), CAS [[700874-72-2]]

Produktübersicht

• Artikelname: LY2157299 (LY 2157299, LY-2157299, Galunisertib), CAS [[700874-72-2]]
• Artikelnummer: USB-366899
• Hersteller Artikelnummer: 366899
• Alternativnummer: USB-366899-5,USB-366899-50
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

Synonyms: LY 2157299, LY-2157299, Galunisertib Chemical Name: 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide Molecular Formula: C22 H19 N5 Molecular Weight: 369.4 CAS Number: 700874-72-2 Purity: 98% Applications: FA Appearance: Crystalline solid Description: LY2157299 is a potent inhibitor of Transforming Growth factor-Beta Receptor I (TGF-BetaR). TGF-Beta1 is involved in the control of cell growth, proliferation, differentiation, and apoptosis. LY2157299 is reported to disrupt Smad-2 phosphorylation in Human Umbilical Vein Endothelial Cells (HUVEC) and inhibit the growth and migration of tumor cells. Storage: Soluble in organic solvents such as ethanol and DMSO. DMSO up to 25mg/ml.

Produkteigenschaften

• Molekulargewicht: 369.4
• Reinheit: Highly Purified (~98%)
• Formulierung: Supplied as a crystalline solid.
• CAS Nummer: [700874-72-2]