GZMH, Recombinant, Human, aa19-246, His-Tag (Granzyme H Isoform 1)
Artikelnummer:
USB-369070
Hersteller Artikelnummer:
369070
Alternativnummer:
USB-369070-10
Hersteller:
US Biological
Kategorie:
Molekularbiologie
GZMH, as known as granzyme H isoform 1, is a member of the granzyme family of serine proteases found specifically in the granules of cytotoxic Tlymphocytes (CTL) and natural killer (NK) cells. The more abundant expression of this protein than granzyme B in NK cells suggests that granzyme H may complement the pro-apoptotic function of granzyme B in this cell type. Source: Recombinant protein corresponding to aa19-246 from human GZMH, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~26.2kD (234aa) 28-40kD (SDS-PAGE under reducing conditions) Amino Acid Sequence: EEIIGGHEAK PHSRPYMAFV QFLQEKSRKR CGGILVRKDF VLTAAHCQGS SINVTLGAHN IKEQERTQQF IPVKRPIPHP AYNPKNFSND IMLLQLERKA KWTTAVRPLR LPSSKAQVKP GQLCSVAGWG YVSMSTLATT LQEVLLTVQK DCQCERLFHG NYSRATEICV GDPKKTQTGF KGDSGGPLVC KDVAQGILSY GNKKGTPPGV YIKVSHFLPW IKRTMKRLHH HHHH Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
