IFNL1, as known as interferon lambda-1, is a secreted protein which belongs to the IL28/29 family. It is a cytokine with immunomodulatory activity. This protein is highly similar in amino acid sequence to the IL28. Also, it plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. It may play a role in antiviral immunity. Source: Recombinant protein corresponding to human IFNL1, fused to His-tag at C-terminal, expressed in insect cell. Molecular Weight: ~20.8kD (187aa) 18-28kD (SDS-PAGE under reducing conditions) Amino Acid Sequence: GPVPTSKPTT TGKGCHIGRF KSLSPQELAS FKKARDALEE SLKLKNWSCS SPVFPGNWDL RLLQVRERPV ALEAELALTL KVLEAAAGPA LEDVLDQPLH TLHHILSQLQ ACIQPQPTAG PRPRGRLHHW LHRLQEAPKK ESAGCLEASV TFNLFRLLTR DLKYVADGNL CLRTSTHPES THHHHHH Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
