IL7, as known as interleukin-7 isoform 1, is a cytokine of the hemopoietin family that plays important roles in lymphocyte differentiation, proliferation, and survival. This protein is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells but is not produced by normal lymphocytes. Recombinant protein corresponding to aa26-177 from human IL7, fused to His-Tag at C-terminal, expressed in insect cell. Accession: NP_000871. Molecular Weight: ~18.4kD (161aa) 18-28kD (SDS-PAGE under reducing conditions.) Amino Acid Sequence: ADPDCDIEGK DGKQYESVLM VSIDQLLDSM KEIGSNCLNN EFNFFKRHIC DANKEGMFLF RAARKLRQFL KMNSTGDFDL HLLKVSEGTT ILLNCTGQVK GRKPAALGEA QPTKSLEENK SLKEQKKLND LCFLKRLLQE IKTCWNKILM GTKEHHHHHH H Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
