LY9, as known as T-lymphocyte surface antigen Ly-9 isoform, is a type 1 transmembrane glycoprotein in the SLAM subgroup of the CD2 family. This protein consists of an extracellular domain with two lg-like V-set and two lg-like truncated C2-set domains. It is expressed on T and B cells, thymocytes, and more weakly on NK cells. Homophilic binding between LY9 molecules is mediated by the N-terminal lg-like domain. Also, this protein knockout mice show minimally impaired immune responses, suggesting functional redundancy with other molecules. Source: Recombinant protein corresponding to aa48-454 from human LY9, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~45.9kD (416aa) 40-57kD (SDS-PAGE under reducing conditions.) Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
