CD3G, also known as T-cell surface glycoprotein CD3 gamma chain, is associated on the T cell surface with a complex of protein called CD3. The protein is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal transduction pathways. Defects in this gene are associated with T cell immunodeficiency. Source: Recombinant protein corresponding to aa23-116 from human CD3G, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~11.8kD (103aa) 13.5-18kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATISHHH HHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.