CD79A, also known as B-cell antigen receptor complex-associated protein alpha chain isoform 1, is a membrane-spanning, signal-transducing components of the B-cell receptor. It plays multiple and diverse roles in B cell development and function. It can be a cause of agammaglobulinemia. It is upregulated on MDSCs and activated in response to soluble factors secreted by tumor cells. It plays a functional role in the tumor promoting effects of myeloid cells, and may represent a novel target for cancer therapy. Recombinant protein corresponding to aa33-143 from human CD79A, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~13.6kD (119aa), 18-28kD (SDS-PAGE under reducing conditions) Amino Acid Sequence: LWMHKVPASL MVSLGEDAHF QCPHNSSNNA NVTWWRVLHG NYTWPPEFLG PGEDPNGTLI IQNVNKSHGG IYVCRVQEGN ESYQQSCGTY LRVRQPPPRP FLDMGEGTKN RLEHHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
