EDA2R, Recombinant, Human, aa1-138, hIgG-His-Tag (Tumor Necrosis Factor Receptor Superfamily Member 27, EDA-A2R, EDAA2R, TNFRSF27, XEDAR)

Produktübersicht

• Artikelname: EDA2R, Recombinant, Human, aa1-138, hIgG-His-Tag (Tumor Necrosis Factor Receptor Superfamily Member 27, EDA-A2R, EDAA2R, TNFRSF27, XEDAR)
• Artikelnummer: USB-377793
• Hersteller Artikelnummer: 377793
• Alternativnummer: USB-377793-50
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

EDA2R also known as Tumor necrosis factor receptor superfamily member 27 isoform 2, is a transmembrane protein in the TNF receptor superfamily. This protein itself is strongly associated with androgenetic alopecia (male hair loss). It is widely expressed, notably in embryonic basal epidermal cells and maturing hair follicles. Even though it does not contain a cytoplasmic death domain, it can associate with Fas and induce EDA-A2 dependent apoptosis. Source: Recombinant protein corresponding to aa1-138 from human EDA2R, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~42.5kD (380aa), 40-57kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPMDCQENE YWDQWGRCVT CQRCGPGQEL SKDCGYGEGG DAYCTACPPR RYKSSWGHHR CQSCITCAVI NRVQKVNCTA TSNAVCGDCL PRFYRKTRIG GLQDQECIPC TKQTPTSEVQ CAFQLSLVEA DAPTVPPQEA TLEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SRDELTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGKHHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Produkteigenschaften

• Molekulargewicht: 42.5
• NCBI: 001229239
• UniProt: Q9HAV5
• Reinheit: ~90% (SDS-PAGE)
• Formulierung: Supplied as a liquid in PBS, pH 7.4, 1mM DTT, 20% glycerol.