RNASE3, Recombinant, Human, aa28-160, His-Tag (Ribonuclease RNase A Family 3, ECP, RAF1, RNS3)

Produktübersicht

• Artikelname: RNASE3, Recombinant, Human, aa28-160, His-Tag (Ribonuclease RNase A Family 3, ECP, RAF1, RNS3)
• Artikelnummer: USB-377954
• Hersteller Artikelnummer: 377954
• Alternativnummer: USB-377954-50
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

RNASE3, also known as Ribonuclease RNase A family 3, located in the eosinophil primary matrix. It released during degranulation of eosinophils. This protein is related to inflammation and asthma because in these cases, there are increased levels of ECP in the body. It is a potent cytotoxic protein capable of killing cells of guinea pig tracheal epithelium, mammalian leukemia, epidermis carcinoma, and breast carcinoma, as well as non- mammalian cells such as parasites, bacteria, and viruses. Source: Recombinant protein corresponding to aa28-160 from human RNASE3 protein, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~16.6kD (142aa), 18-28kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPRPPQFTR AQWFAIQHIS LNPPRCTIAM RAINNYRWRC KNQNTFLRTT FANVVNVCGN QSIRCPHNRT LNNCHRSRFR VPLLHCDLIN PGAQNISNCR YADRPGRRFY VVACDNRDPR DSPRYPVVPV HLDTTIHHHH HH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Produkteigenschaften

• Molekulargewicht: 16.6
• NCBI: 96060
• UniProt: P12724
• Reinheit: ~90% (SDS-PAGE)
• Formulierung: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.