10-Hydroxy-11-methoxycamptothecin-d3 is the labelled version of 10-Hydroxy-11-methoxycamptothecin (H949833) which can be obtained from (S)-(+)-Camptothecin (C175150) which is an antitumor alkaloid. It binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent. Molecular Formula: C21H15D3N2O6 Molecular Weight: 397.4 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
397.4
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