Aprepitant-d4 is a labeled analogue of Aprepitant (A729800), A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Aprepitant-d4 is a potential treatment for chemotherapy induced nausea and vomiting. Molecular Formula: C23H17D4F7N4O3 Solubility: DMSO (Slightly), Methanol (Slightly) Molecular Weight: 538.45000000000005 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
538.45
Formulierung:
Supplied as a White Solid
CAS Nummer:
[1133387-60-6]
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