Atrasentan is a selective antagonist of the endothelin-A (ETA) receptor and binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation. Used in studies related to glomerular disease and diabetic nephropathy. Synonyms: ABT-627, A-147627, (+)-A 127722, (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic Acid, (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic Acid CAS No: 173937-91-2 Molecular Formula: C29H38N2O6 Molecular Weight: 510.62 Appearance: White to off-white solid Purity: 99% (HPLC) NMR, C NMR, MS: Conforms to reference Melting Point: 121-126C Solubility: DMSO (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
510.62
Reinheit:
99% (HPLC)
Formulierung:
White to off-white solid
CAS Nummer:
[173937-91-2]
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